Books about Toxicity from Amazon.com

Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process.

The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties.

* Serves as an essential working handbook aimed at scientists and students in medicinal chemistry
* Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies
* Discusses improvements in pharmacokinetics from a practical chemist's standpoint.
Price: $78.59 [Notify me when price goes down.]

Long-established as the gold standard in the field, Casarett and Doull's Toxicology is now available in a new Sixth Edition that equips you with an unsurpassed treatment of modern toxicology, including the principles, concepts, mechanisms, and modes of thought that are the foundation of the discipline.

Comprehensive and completely up to date, the new edition of Casarett and Doull's Toxicology remains your best source for the latest breakthroughs in this fast-changing field.
* The new edition of this gold standard in the field is more valuable than ever
* Detailed coverage of the advances in molecular biology and pharmacogenetics
* Expanded coverage of risk assessment
* Coverage of online references, in addition to traditional print journal and review articles
* New chapter outlines
* New 2-color design.
Price: $91.89 [Notify me when price goes down.]

Hair Test Interpretation: Finding Hidden Toxicities is a practical book. The book starts out telling you how to interpret a hair test for mercury and other heavy metals. It provides a step by step discussion of this with figures to make this easy to do. It gives examples using actual hair test results from real people. Mercury interferes with how the hair element results come out ? mercury is often low and other minerals take unusual values. It is crucial for proper hair test interpretation to know how to recognize mercury’s characteristic signature. Mercury often causes retention of certain minerals. Arsenic, antimony, tin, titanium, zirconium and aluminum are elements many people retain too much of when they really have a mercury problem. Hair tests are worth doing because a surprising number of people diagnosed with incurable chronic health conditions actually turn out to have a heavy metal problem. Heavy metal problems are easy to correct. Hair testing allows the underlying problem to be identified and the chronic health condition often disappears with proper detoxification..
Price: $39.50 [Notify me when price goes down.]

Univ. of Arizona, Tucson. A collection of recent research on environmental health and toxic exposures, designed to educate and aid public health clinicians and decision makers. Covers individual organs and systems, and prevention and safety issues. Revised edition of Hazardous Materials Toxicology, c1992. DNLM: Hazardous Substances--toxicity. .
Price: $160.00 [Notify me when price goes down.]

Integrating ecotoxicological concepts across a range of hierarchical levels, Ecotoxicology: A Comprehensive Treatment focuses on the paradigms and fundamental themes of ecotoxicology while providing the detail and practical application of concepts often found in more specialized books. By synthesizing the best qualities of a general textbook and the narrower, more specific scope of a technical reference, the authors create a volume flexible enough to cover a variety of instructional vantages and thorough enough to engender a respect for the importance of understanding and integrating concepts from all levels of biological organization.

Divided into six sections, the book builds progressively from the biomolecular level toward a discussion of effects on the global biosphere. It begins with the fundamentals of hierarchical ecotoxicology and vantages for exploring ecotoxicological issues. The second section introduces organismal ecotoxicology and examines effects to biochemicals, cells, organs, organ systems, and whole organisms, and bioaccumulation and bioavailability of contaminants. Population ecotoxicology, section three, places the discussion in the larger context of entire populations by analyzing epidemiology, population dynamics, demographics, genetics, and natural selection.

Section four encompasses issues of community ecotoxicology. This section presents biotic and abiotic factors influencing communities, biomonitoring and community response, and the application of multimetric and multivariate approaches. Section five evaluates the entire ecosystem by describing assessment approaches, identifying patterns, analyzing relationships between species, and reviewing the effects of global atmospheric stressors. A detailed conclusion integrating the concepts discussed and promoting a balanced assessment of the overarching paradigms rounds out the coverage in section six..
Price: $120.34 [Notify me when price goes down.]

Who would expect that making a profit would be more important than people's health and their lives? Yet, this is exactly the case in the cosmetics industry. Cosmetics and toiletries are laden with toxic chemicals, many carcinogenic Makeup, hair coloring products, baby powder, shaving cream, mouthwash and toothpaste are just a few of the products that contain cancer-causing ingredients. Even products that are supposed to be gentle and mild for babies often contain toxic, irritating chemicals.

Dying to Look Good tells you if the cosmetic and personal care products you're buying contain dangerous ingredients. It reveals what manufacturers don't want you to know about their products and shows you how to find the truth behind deceptive product packaging. You will learn how to confidently read labels so you know how safe your cosmetics and toiletries are.

This book classifies over 1200 cosmetic ingredients according to safety, whether they may cause allergic reactions, whether they have been reviewed by the Cosmetic Ingredient Review Panel and if they are approved or recognized as safe by the FDA. It also lists over 750 cosmetic and personal care products that have been evaluated as "safe." In just seconds, you can find out if an ingredient in the product you're buying is harmful and you can identify safer products for yourself and your family..
Price: $24.23 [Notify me when price goes down.]

Handbook of the Toxicology of Metals is the standard reference work for physicians, toxicologists and engineers in the field of environmental and occupational health. This new edition is a comprehensive review of the effects on biological systems from metallic elements and their compounds. An entirely new structure and illustrations represent the vast array of advancements made since the last edition. Special emphasis has been placed on the toxic effects in humans with chapters on the diagnosis, treatment and prevention of metal poisoning. This up-to-date reference provides easy access to a broad range of basic toxicological data and also gives a general introduction to the toxicology of metallic compounds.

* Covers up-to-date toxicological information on 31 metallic elements and their compounds, each in a separate chapter
* New chapters on general chemistry, biological monitoring and biomarkers, essential metals, principles for prevention of the toxic effects of metals, and more.
Price: $234.51 [Notify me when price goes down.]

This book and companion CD is a complete guide to detailed biomedical and Chinese medicine information on over 100 of the most important formulas you use every day.

The companion CD is searchable by formula name, herb name, or class of Western drug.

Feel more secure prescribing Chinese herbal formulas to a patient taking Western Pharmaceuticals.

Know the potential side effects before prescribing a Chinese herbal formula to a patient taking Western pharmaceuticals.

Be able to communicate more effectively with Western MDs about the herbs your patients are taking..
Price: $36.00 [Notify me when price goes down.]