Books about Aerodigestive from Amazon.com

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Price: $103.97 [Notify me when price goes down.]

The name Wolfgang Steiner is synonymous with transoral laser microsurgery for head and neck cancer. He has tirelessly promoted this innovative technique throughout the world and his clinic is considered the pioneering center in Europe. Thousands of students and practitioners have benefited from his teaching and lectures, allowing them to treat selected patients more safely and effectively than ever thought possible.

Now for the first time, you have at your fingertips Dr. Steiner's detailed, step-by-step techniques for transoral laser microsurgery of the head and neck, showing how to excise tumors, preserve the larynx and other key structures, and dramatically decrease mortality. You will learn the insights and technical refinements that allow you to tailor your surgery to the extent of the cancer, even eradicating it in certain localized areas. You will see how to work in a fraction of the time, avoid complex throat and neck reconstructions, preserve voice structures, and greatly enhance the patient's quality of life.

Special features of this landmark book include:

- Written by the developers of this innovative, minimally invasive technique

- 300 endoscopic color images and explanatory drawings illustrate the diagnostic and surgical procedures on a step-by-step basis

- Ideal for students as well as for practitioners seeking to broaden their treatment options

- Offers an introduction to a rapidly growing standard in the field of head and neck oncology.

For the beginner as well as the experienced surgeon, this book offers masterful guidance on using modern laser technology to perform conservative laryngeal and other head and neck cancer surgeries, resulting in well-documented, lower morbidity rates. It will upgrade and enrich your skills and open a wide range of treatment options that you can offer your patients..
Price: $132.40 [Notify me when price goes down.]

The authors provide a guideline for the anatomical dissection of specimens from oral and sinonasal cavities, pharynx and larynx. This is achieved through illustrations and colour photographs that combine drawings of tumours at various anatomical subsites together with the respective operations, the specimens thus obtained and the way to dissect these specimens. The dissection of surgical specimens from the upper aerodigestive tract is often difficult due to the anatomically complicated nature of this area. Local environment dictates routes of tumour spread and surgical margins at risk and those differ for various subsites within this part of the body. Moreover, adequate investigation of surgical specimens of the upper aerodigestive tract requires knowledge of the various types of surgical procedures. This should provide data that enable the surgeon to correlate preoperatively performed diagnostic imaging with the macroscopical findings postoperatively obtained..
Price: $79.83 [Notify me when price goes down.]

This digital document is an article from Alcohol Research & Health, published by Thomson Gale on September 22, 2006. The length of the article is 5373 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Cancer risk associated with alcohol and tobacco use: focus on upper aero-digestive tract and liver.(HEALTH RISKS)
Author: Claudio Pelucchi
Publication:Alcohol Research & Health (Magazine/Journal)
Date: September 22, 2006
Publisher: Thomson Gale
Volume: 29 Issue: 3 Page: 193(6)

Distributed by Thomson Gale.
Price: $9.95 [Notify me when price goes down.]

This digital document is a journal article from Mut.Res.-Genetic Toxicology and Environmental Mutagenesis, published by Elsevier in 2004. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
The carcinogenic potential of xenobiotics and possible confounders are often difficult to differentiate in in vivo studies. In contrast, in vitro studies allow investigation of the impact of carcinogens on human target cells under standardized conditions. The aim of the present study is to demonstrate whether three-dimensional mini organ-cultures (MOCs) of human inferior nasal turbinate epithelia may represent a useful model to study genotoxic effects of xenobiotics in vitro. Culture of mini organs was performed by cutting 1mm^3 pieces from fresh specimens of inferior nasal turbinates. After a period of 5-6 days the specimens were fully covered with epithelium. On days 7, 9, and 11 of culture, intact MOCs from 25 tissue donors were incubated with dimethyl sulfoxide (DMSO) as a negative control, or with mono(2-ethylhexyl) phthalate (MEHP), benzo[a]pyrene-7,8-diol-9,10-epoxide (BPDE), or N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). On days 7 and 11, MOCs were analyzed by the alkaline Comet assay to detect DNA-single-strand breaks, alkali-labile sites and incomplete excision-repair sites. DNA migration after single exposure of non-cultivated fresh specimens was also analyzed. In order to detect regimen-specific effects, DNA fragmentation after single exposure of intact MOCs was compared with that of cells after separation of MOCs on day 7 of culture and consecutive exposure of individual cells. Significant DNA migration as a measure of DNA single-strand breaks, alkali-labile sites and incomplete excision repair sites, was found after electrophoresis due to single and triple exposure of MOCs to MEHP, BPDE and MNNG. Triple exposure of MOCs compared to single exposure revealed no difference after exposure to DMSO or MEHP, and an increased migration after exposure to BPDE and MNNG. When single exposure of isolated cells from fresh specimens was compared with that of intact MOCs, DMSO and MNNG had no significantly different effect, whereas exposure to MEHP or BPDE caused a reduced migration in cells from MOCs. When exposure of isolated cells harvested from MOCs was compared with exposure of intact MOCs, MEHP and BPDE caused a significantly lower DNA migration in intact MOCs. MOCs provide an in vitro model suitable for the assessment of genotoxic effects of environmental pollutants both after single or repetitive exposure. Due to the intact structure of the exposed mucosa this model may be a helpful tool in mimicking the in vivo situation in ecogenotoxicology studies. .
Price: $8.95 [Notify me when price goes down.]