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A Life Decoded: My Genome: My Life
The triumphant true story of the man who achieved one of the greatest feats of our era—the mapping of the human genome Growing up in California, Craig Venter didn’t appear to have much of a future. An unremarkable student, he nearly flunked out of high school. After being drafted into the army, he enlisted in the navy and went to Vietnam, where the life and death struggles he encountered as a medic piqued his interest in science and medicine. After pursuing his advanced degrees, Venter quickly established himself as a brilliant and outspoken scientist. In 1984 he joined the National Institutes of Health, where he introduced novel techniques for rapid gene discovery, and left in 1991 to form his own nonprofit genomics research center, where he sequenced the first genome in history in 1995. In 1998 he announced that he would successfully sequence the human genome years earlier, and for far less money, than the government-sponsored Human Genome Project would— a prediction he kept in 2001. A Life Decoded is the triumphant story of one of the most fascinating and controversial figures in science today. In his riveting and inspiring account Venter tells of the unparalleled drama of the quest for the human genome, a tale that involves as much politics (personal and political) as science. He also reveals how he went on to be the first to read and interpret his own genome and what it will mean for all of us to do the same. He describes his recent sailing expedition to sequence microbial life in the ocean, as well as his groundbreaking attempt to create synthetic life. Here is one of the key scientific chronicles of our lifetime, as told by the man who beat the odds to make it happen..
Price: $6.97
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The Murder of Nikolai Vavilov: The Story of Stalin's Persecution of One of the Great Scientists of the Twentieth Century
In The Murder of Nikolai Vavilov, acclaimed journalist and author Peter Pringle recreates the extraordinary life and tragic end of one of the great scientists of the twentieth century. In a drama of love, revolution, and war that rivals Pasternak's Dr. Zhivago, Pringle tells the story of a young Russian scientist, Nikolai Vavilov, who had a dream of ending hunger and famine in the world. Vavilov's plan would use the emerging science of genetics to breed super plants that could grow anywhere, in any climate, in sandy deserts and freezing tundra, in drought and flood. He would launch botanical expeditions to find these vanishing genes, overlooked by early farmers ignorant of Mendel's laws of heredity. He called it a "mission for all humanity." To the leaders of the young Soviet state, Vavilov's dream fitted perfectly into their larger scheme for a socialist utopia. Lenin supported the adventurous Vavilov, a handsome and seductive young professor, as he became an Indiana Jones, hunting lost botanical treasures on five continents. In a former tsarist palace in what is now St. Petersburg, Vavilov built the world's first seed bank, a quarter of a million specimens, a magnificent living museum of plant diversity that was the envy of scientists everywhere and remains so today. But when Lenin died in 1924 and Stalin took over, Vavilov's dream turned into a nightmare. This son of science was from a bourgeois background, the class of society most despised and distrusted by the Bolsheviks. The new cadres of comrade scientists taunted and insulted him, and Stalin's dreaded secret police built up false charges of sabotage and espionage. Stalin's collectivization of farmland caused chaos in Soviet food production, and millions died in widespread famine. Vavilov's master plan for improving Soviet crops was designed to work over decades, not a few years, and he could not meet Stalin's impossible demands for immediate results. In Stalin's Terror of the 1930s, Russian geneticists were systematically repressed in favor of the peasant horticulturalist Trofim Lysenko, with his fraudulent claims and speculative theories. Vavilov was the most famous victim of this purge, which set back Russian biology by a generation and caused the country untold harm. He was sentenced to death, but unlike Galileo, he refused to recant his beliefs and, in the most cruel twist, this humanitarian pioneer scientist was starved to death in the gulag. Pringle uses newly opened Soviet archives, including Vavilov's secret police file, official correspondence, vivid expedition reports, previously unpublished family letters and diaries, and the reminiscences of eyewitnesses to bring us this intensely human story of a brilliant life cut short by anti-science demagogues, ideology, censorship, and political expedience..
Price: $6.75
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The Sanctuary
In the powerful new thriller from the author of the international bestseller The Last Templar, a geneticist and a CIA agent on a deadly quest to find the most dangerous book in the world discover a secret that has destroyed everyone in its path for centuries Naples, 1750. In the dead of night, three men with swords burst into the palazzo of a marquis. Their leader, the Prince of San Severo, accuses the marquis of being an imposter, and demands to know a secret only the marquis harbors. In the fight that ensues, the false marquis escapes over the rooftops of Naples, leaving behind a burning palazzo and a raging prince now obsessed with finding his quarry at any cost. Baghdad, 2003. An army unit on a routine mission makes a horrifying discovery: a state- of-the-art, concealed lab where dozens—men, women, children—have died, the subjects of gruesome experiments. The mysterious scientist they were after, a man believed to be working on a bioweapon and known only as the hakeem—the doctor—escapes, taking with him the startling truth about his work. A puzzling clue is left behind: a circular symbol of a snake feeding on its own tail. As the power of the symbol comes to light, revealing the centuries of destruction left in its wake, one unsuspecting woman stands at the center of a conspiracy that could change the world forever. In the masterful hands of international bestseller Raymond Khoury, The Sanctuary delivers the same rapid-fire suspense and provocative scholarship that made The Last Templar a coast-to-coast blockbuster..
Price: $4.69
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The Geneticist Who Played Hoops with My DNA: . . . And Other Masterminds from the Frontiers of Biotech
Combining myth, biography, and wit -- a highly original depiction of cutting-edge science -- told through the scientists who are rewriting life on earth While the future of human existence is literally being forged by today's genetic scientists and biotechnology leaders, the media, policymakers, ethicists, and fellow scientists alike have not been adequately communicating the tremendous potential that is contained in these individuals' work. With the public only vaguely aware of what is really happening, a new coterie of geniuses, tinkerers, tycoons, and genetic soothsayers are -- for better or worse -- about to alter life on earth forever. Now award-winning journalist David Ewing Duncan has written an insightful narrative about science and personality, delving into stem cell research, cloning, bioengineering, extending life span, and genetics by telling the stories of the characters at the fulcrum of the science. Calling to mind age-old stories and myths -- Prometheus, Faustus, Eve, and Frankenstein -- Duncan asks the question: Can we trust these scientists? Duncan has spent the last three years reporting on and studying these masterminds, from the co-solver of the DNA structure James Watson to a man who is creating synthetic life, Craig Venter. The Geneticist Who Played Hoops with My DNA tells their stories, revealing their quirky, fascinating, and sometimes vaguely unsettling personas as a way to understand their science and the implications of their work. .
Price: $4.79
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Gregor Mendel: The Friar Who Grew Peas
The only picture book available about the father of genetics and his pea plants!How do mothers and fathers—whether they are apple trees, sheep, or humans—pass down traits to their children? This question fascinated Gregor Mendel throughout his life. Regarded as the world’s first geneticist, Mendel overcame poverty and obscurity to discover one of the fundamental aspects of genetic science: animals, plants, and people all inherit and pass down traits through the same process, following the same rules. Living the slow-paced, contemplative life of a friar, Gregor Mendel was able to conceive and put into practice his great experiment: growing multiple generations of peas. From observing yellow peas, green peas, smooth peas, and wrinkled peas, Mendel crafted his theory of heredity—years before scientists had any notion of genes. Children will be inspired by Gregor’s neverending search for knowledge, and his famous experiments are easy to understand as an introduction to genetics. .
Price: $7.58
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Immunity (Dr. Alexandra Blake Novels)
One bizarre death is just that---a death. Two? Could be a coincidence But in Lori Andrews’s latest thriller, geneticist Dr. Alexandra Blake discovers something much more dangerous than a killer---an epidemic.
Taking a break from decoding the genetic sequence of a tropical disease, Alex takes on an investigation into the gruesome and unexplained death of a DEA agent on a mob stakeout in New Mexico. Within hours, she uncovers similar deaths throughout the Southwest. Is it a naturally occurring epidemic or has a lethal bioweapon been released in the United States?
With the nation’s attention focused on a provocative presidential race, Alex’s attempts to warn Homeland Security fail. Only with the help of a rogue DEA agent and a cutting-edge supercomputer will she and the rest of her team at the Armed Forces Institute of Pathology stand a chance of putting an end to the devastation before public hysteria rages out of control.
From Alex’s lab to the closed rooms of a killer’s mind, Immunity maps the perfect sequence for an infectious, edge-of-your-seat thriller. .
Price: $12.47
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Francis Crick: Discoverer of the Genetic Code (Eminent Lives) (rough edge)
Francis Crick, who died at the age of eighty-eight in 2004, will be bracketed with Galileo, Darwin, and Einstein as one of the great scientists of all time. Between 1953 and 1966 he made and led a revolution in biology by discovering, quite literally, the secret of life: the digital cipher at the heart of heredity that distinguishes living from non-living things--the genetic code. His own discoveries--though he always worked with one other partner and did much of his thinking in conversation--include not only the double helix but the whole mechanism of protein synthesis, the three-letter nature of the code, and much of the code itself. Matt Ridley's biography traces Crick's life from middle-class mediocrity in the English Midlands, through a lackluster education and six years designing magnetic mines for the Royal Navy, to his leap into biology at the age of thirty-one. While at Cambridge, he suddenly began to display the unique visual imagination and intense tenacity of thought that would allow him to see the solutions to several great scientific conundrums--and to see them long before most biologists had even conceived of the problems. Having set out to determine what makes living creatures alive and having succeeded, he immigrated at age sixty to California and turned his attention to the second question that had fascinated him since his youth: What makes conscious creatures conscious? Time ran out before he could find the answer. Discover More Eminent Lives  Freud: Inventor of the Modern Mind by Peter Kramer |  Muhammad: A Prophet for Our Time by Karen Armstrong |  Machiavelli: Philosopher of Power by Ross King |  George Washington: The Founding Father by Paul Johnson |  Thomas Jefferson: Author of America by Christopher Hitchens |  Alexis de Tocqueville: Democracy's Guide by Joseph Epstein |
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Price: $2.30
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Soul
Learner’s The Witch of Cologne is an erotically-charged novel of people swept inexorably along by events they could not control In Soul, Learner relates the story of Lavinia and Julia Huntington, passionate women trapped in emotional whirlpools that threaten to drown them and everyone they love. In 19th century Britain, Lavinia is married to an older man who seems to appreciate her lively curiosity. Lavinia proves to be an apt pupil in both the study and the bedroom, glorying in the pleasures of the physical. In 21st century Los Angeles, geneticist Julia is trying to identify people who can kill without remorse. Stunned to discover that she seems to possess the trait she is looking for, Julia is reassured of her emotions by her intense passion for her husband and her delight in her pregnancy. In the past, Lavinia’s desire for her husband grows, but his cools as he becomes fascinated with another. In the present, Julia’s love overwhelms her husband, who leaves her. Lavinia and Julia feel the tortures of passion unspent. Cold logic tells them that the deaths of their tormentors will bring them peace. Separated by a hundred years, two Huntington women face the same decision. Their choices will echo far into the future. .
Price: $3.99
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Bioinformatics for Geneticists: A Bioinformatics Primer for the Analysis of Genetic Data
A fully revised version of the successful First Edition, this one-stop reference book enables all geneticists to improve the efficiency of their research. The study of human genetics is moving into a challenging new era. New technologies and data resources such as the HapMap are enabling genome-wide studies, which could potentially identify most common genetic determinants of human health, disease and drug response. With these tremendous new data resources at hand, more than ever care is required in their use. Faced with the sheer volume of genetics and genomic data, bioinformatics is essential to avoid drowning true signal in noise. Considering these challenges, Bioinformatics for Geneticists, Second Edition works at multiple levels: firstly, for the occasional user who simply wants to extract or analyse specific data; secondly, at the level of the advanced user providing explanations of how and why a tool works and how it can be used to greatest effect. Finally experts from fields allied to genetics give insight into the best genomics tools and data to enhance a genetic experiment. Hallmark Features of the Second Edition: - Illustrates the value of bioinformatics as a constantly evolving avenue into novel approaches to study genetics
- The only book specifically addressing the bioinformatics needs of geneticists
- More than 500f chapters are completely new contributions
- Dramatically revised content in core areas of gene and genomic characterisation, pathway analysis, SNP functional analysis and statistical genetics
- Focused on freely available tools and web-based approaches to bioinformatics analysis, suitable for novices and experienced researchers alike
Praise from the reviews: "This book may really help to get geneticists and bioinformaticians on 'speaking-terms'... contains some essential reading for almost any person working in the field of molecular genetics." EUROPEAN JOURNAL OF HUMAN GENETICS "... an excellent resource... this book should ensure that any researcher's skill base is maintained." GENETICAL RESEARCH Bioinformatics for Geneticists, Second Edition describes the key bioinformatics and genetic analysis processes that are needed to identify human genetic determinants. The book is based upon the combined practical experience of domain experts from academic and industrial research environments and is of interest to a broad audience, including students, researchers and clinicians working in the human genetics domain..
Price: $66.93
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