Books about Lymphocyte from Amazon.com

Atopic eczema (eczema, atopic dermatitis, diffuse neurodermatitis, endogenous eczema) is one of the most common skin diseases of our time—not only in childhood The prevalence of this disease has increased dramatically over the past decades, although the reasons for this increase are not known. Eczema occurs anywhere in the world, not only in industrialized countries. It occurs at any age, not only in childhood, and approximately two-thirds of children affected will suffer from this disease when they are grown up.

Written by leading experts in their field, this second edition of the excellent handbook of atopic eczema comprises the state of the art in pathophysiology, clinical medicine, and therapeutic management. It demonstrates that there is no simple "miracle" cream, pill, or diet for this disease, but that a disturbed barrier function can only be repaired by adequate and individualized skin care. It also shows how unspecific anti-inflammatory treatment has to be individually tailored according to body area affected, patient age, and severity of skin lesions. All physicians treating patients with atopic eczema will find this book most helpful in their painstaking search for the individual causal or eliciting factors, which is the only basis for rational treatment and prevention of this disease.

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Price: $131.00 [Notify me when price goes down.]

In recent years, major developments have been made in understanding various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. A role and mechanism of DNA repair proteins in somatic hypermutation has been elucidated. Genetic mutation studies have been instrumental in providing insight into some of the mechanisms involved in targeting CSR to various switch DNA regions located upstream of C region genes, especially a role of AID motifs, transcription, and R-loops. Recent studies support a dominant role of receptor editing in central B cell tolerance and signaling pathways that regulate receptor editing in self-reactive and non-self-reactive immature B cells. These were some of the topics of discussion at the 11th International Conference on B cell Biology. These proceedings highlight recent developments in lymphocyte development, Ig gene rearrangements and somatic hypermutation, chromatin structure modification, B lymphocyte signaling and fate, receptor editing, and autoimmunity.

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Price: $83.85 [Notify me when price goes down.]

Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. It is also the prototype of B-cell chronic lymphoid malignancies and of their ramifications within the fields of hematology, immunology and oncology. For a long time the Cinderella of lymphoid malignancies CLL has now become the focus of major interest and an increasing number of investigators from different areas, including genetics, molecular biology, basic and applied immunology are becoming actively engaged in the investigation of CLL. Clinicians are considering CLL as a very interesting target of many projects which aim at translating the new and exciting developments of basic science into effective new approaches to the patient.

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Price: $101.00 [Notify me when price goes down.]

Epithelial defense against infectious agents relies on the recognition of microbial products by pattern recognition receptors and the local production of antimicrobial peptides. This book provides a state-of-the-art overview of the basic characteristics and clinical relevance of antimicrobial peptides, with special emphasis on their role in skin, intestinal and lung inflammation. The evolutionary significance of antimicrobial peptides is highlighted by an in-depth analysis of their structure, activity and gene regulation in Drosophila melanogaster. Toll-like receptors are an important class of pattern recognition receptors, whose roles in recognizing bacterial molecular patterns and in the intracellular signalling pathways involved in the differentiation and function of dendritic cells are discussed. Finally, this book also addresses the role of intraepithelial lympho cytes in epithelial defense, notably of gammadelta T cells which form a link between innate and adaptive immune.
Price: $15.00 [Notify me when price goes down.]

Specifically it will cover molecular basis for hematopoietic stem cell commitment and terminal differentiation. Recent discoveries in role of transcription factors and the influence of cytokines will be discussed in the context of human and mouse hematopoietic lineages. In addition signal transduction pathways regulating proliferation, differentiation and apoptosis will be presented in the volume. Finally, the volume will cover recent advances in targeting signal transduction pathways in treatment of hematopoietic disease, including utilization of hematopoietic cells in the clinical setting.

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Price: $122.13 [Notify me when price goes down.]

This digital document is a journal article from Mut.Res.-Genetic Toxicology and Environmental Mutagenesis, published by Elsevier in . The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.

Description:
The evidence for genotoxic potential of formaldehyde (FA) in humans is insufficient and conflicting. We previously reported a higher frequency of micronuclei in nasal and oral exfoliative cells from students exposed to formaldehyde vapor for short-term. To further evaluate the genetic effects of long-term occupational exposure to FA and short-term exposure to FA of indoor sources, the frequencies of micronuclei (MN) in nasal mucosa cells, sister chromatid exchanges (SCEs) of peripheral lymphocytes, and the lymphocyte subsets were evaluated in 18 non-smoking workers (mean exposure duration was 8.6 years) in an FA factory and 16 non-smoking waiters exposed to FA for 12 weeks in a ballroom. A non-smoking student group without occupational exposure (n=23) to FA was used as control. The 8h time-weighted average (TWA) concentrations of formaldehyde was 0.985+/-0.286mg/m^3 with the ceiling exposure concentration of 1.694mg/m^3 in the workshop, and 0.107+/-0.067mg/m^3 in the ballroom (5h TWA). Higher frequencies of micronuclei per thousand cells in nasal mucosa cells of workers versus control (2.70+/-1.50 versus 1.25+/-0.65, p<0.05) and higher frequency of SCEs in peripheral lymphocytes of workers group (8.24+/-0.89 versus 6.38+/-0.41, p<0.05) were observed. Increased frequency of micronuclei in nasal mucosa cells or SCE in peripheral lymphocytes was not found among waiters group. The results suggest that the genotoxic potential of high level FA exposure may have occupational risks in long-term exposure groups. .
Price: $8.95 [Notify me when price goes down.]

This volume in the series will be of value to graduates, scientists, and specialists in the field, looking for a state-of-the-art description of the role of adhesion molecules, chemokines, and the biology of lymphocyte trafficking. Each chapter is written by distinguished experts in the field and provides comprehensive up-to-date references, as well as references to controversial issues in the field.
The Cell Adhesion and Communication series provides graduate students and research scientists in academia, regulatory agencies and industry with an up-to-date description of the current knowledge in a given domain of research. The series encompasses monographs on classes of adhesion molecules and monographs giving a broader functional synopsis on adhesion molecules in a particular system.
Highlights the functional role of adhesion molecules and chemokines in interactions between lymphocytes and endothelium, regulating recirculation and homing. In-depth chapters review key topics such as the.
Price: $149.71 [Notify me when price goes down.]