Books about Synaptic from Amazon.com

In 1996 Joseph LeDoux's The Emotional Brain presented a revelatory examination of the biological bases of our emotions and memories Now, the world-renowned expert on the brain has produced with a groundbreaking work that tells a more profound story: how the little spaces between the neurons-the brain's synapses--are the channels through which we think, act, imagine, feel, and remember. Synapses encode the essence of personality, enabling each of us to function as a distinctive, integrated individual from moment to moment. Exploring the functioning of memory, the synaptic basis of mental illness and drug addiction, and the mechanism of self-awareness, Synaptic Self is a provocative and mind-expanding work that is destined to become a classic..
Price: $9.48 [Notify me when price goes down.]

Now in resplendent color, the new edition continues to define the latest in the scientific understanding of the brain, the nervous system, and human behavior Each chapter is thoroughly revised and includes the impact of molecular biology in the mechanisms underlying developmental processes and in the pathogenesis of disease. Important features to this edition include a new chapter - Genes and Behavior; a complete updating of development of the nervous system; the genetic basis of neurological and psychiatric disease; cognitive neuroscience of perception, planning, action, motivation and memory; ion channel mechanisms; and much more..
Price: $80.00 [Notify me when price goes down.]

It is widely recognized that the neural basis of brain function can be fully understood only by integrating many disciplines at many levels. Studies of synaptic organization are bringing about a quiet revolution in achieving this goal, as documented by this unique book over the past 30 years. In this fifth edition, the results of the mouse and human genome projects are incorporated for the first time. Molecular biologists interested in functional genomics and proteomics of the brain will find answers here to the critical questions: what are the cell and circuit functions of gene products? Also for the first time, the reader is oriented to supporting neuroscience databases. Among the new advances covered are 2-photon confocal laser microscopy of dendrites and dendritic spines, biochemical analyses, and dual patch and multielectrode recordings, applied together with an increasing range of behavioral and gene-targeting methods. Leading experts in the best understood brain regions bring together the molecular, anatomical, functional, and behavioral data in authoritative integrated accounts. The chapters are organized in the same format, covering the neural elements, synaptic connections, basic circuits, physiology, neurotransmitters, neuromodulators, membrane properties, dendritic properties, and with a final section on how the circuits mediate specific behaviors. The uniform framework for each chapter enables the authors to higlight the principles that are common to all regions, as well as the adaptations unique to each, thus serving as a model for understanding the neural basis of behavior..
Price: $58.29 [Notify me when price goes down.]

with simulations and illustrations by Richard Gray


Problem solving is an indispensable part of learning a quantitative science such as neurophysiology. This text for graduate and advanced undergraduate students in neuroscience, physiology, biophysics, and computational neuroscience provides comprehensive, mathematically sophisticated descriptions of modern principles of cellular neurophysiology. It is the only neurophysiology text that gives detailed derivations of equations, worked examples, and homework problem sets (with complete answers).

Developed from notes for the course that the authors have taught since 1983, Foundations of Cellular Neurophysiology covers cellular neurophysiology (also some material at the molecular and systems levels) from its physical and mathematical foundations in a way that is far more rigorous than other commonly used texts in this area..
Price: $57.00 [Notify me when price goes down.]

This book addresses a large variety of models in mathematical and computational neuroscience. It is written for the experts as well as for graduate students wishing to enter this fascinating field of research. The author studies the behaviour of large neural networks composed of many neurons coupled by spike trains. He devotes the main part to the synchronization problem. He presents neural net models more realistic than the conventional ones by taking into account the detailed dynamics of axons, synapses and dendrites, allowing rather arbitrary couplings between neurons. He gives a complete stabile analysis that goes significantly beyond what has been known so far. He also derives pulse-averaged equations including those of the Wilson-Cowan and the Jirsa-Haken-Nunez types and discusses the formation of spatio-temporal neuronal activity pattems. An analysis of phase locking via sinusoidal couplings leading to various kinds of movement coordination is included.

.
Price: $53.00 [Notify me when price goes down.]

It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. This includes a discussion of presynaptic calcium channels, the core proteins of the secretory machinery, and the actions of clostridial toxins and a -latrotoxin, famous for their potency as well as their crucial role in the elucidation of the steps of exocytosis. In the book’s second part, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process. These include ligand-gated ion channels and presynaptic G-protein-coupled receptors. The targets of presynaptic receptors within the exocytosis cascade, and their therapeutic potential, are subjects addressed in the majority of chapters.

.
Price: $377.39 [Notify me when price goes down.]

For decades glial cells were considered relatively passive supporters of nerve function It was accepted that they had important roles to play in the structural, metabolic and trophic support of neurons; however, it is now also known that glial cells are active in the processes of synaptic transmission and information processing. Electrophysiological and optical imaging studies demonstrate that glia not only receive coded information concerning neighbouring synaptic events, but also integrate the exchange of rapid signals with nerve cells and exert modulatory influences at the local and long-range levels. As the specific mechanisms and functional consequences of the glial-synaptic relationship becomes clearer, so the broader relevance of these findings can be understood. The Tripartite Synapse: Glia in Synaptic Transmission introduces the concept of glial cells as active elements of the synapse and the nervous circuitry, describes the experimental evidence supporting this and suggests a revised view of brain activity based on this integrated network of interactive neurons and glia. This is a timely and international review of an exciting new field, and will be of interest to neuroscientists, neurobiologists and cell biologists. The text is supported by a CD containing additional images, movies and animated sequences..
Price: $85.68 [Notify me when price goes down.]

Explores recent discoveries about the synaptic code, explains how electrochemical connections among nerve cells control the mind, and discusses the relationship between synaptic research and human understanding of the larger universe. 20,000 first printing..
Price: $3.49 [Notify me when price goes down.]